Invasive cancer

Liquid Biopsy as a Minimally Invasive Source of Thyroid Cancer Genetic and Epigenetic Alterations

In the blood of cancer patients, some nucleic acid fragments and tumor cells can be found that make it possible to trace tumor changes through a simple blood test called “liquid biopsy”. The main components of liquid biopsy are fragments of DNA and RNA shed by tumors into the bloodstream and circulate freely( ctDNAs and ctRNAs). tumor cells which are shed into the blood (circulating tumor cells...

Invasive cancer of the cervix

Invasive cervical cancer remains the second commonest female malignancy worldwide. Early-stage disease may be asymptomatic. Advances in imaging techniques have improved selection of the appropriate treatment approach. Treatment options vary for each stage. An excisional cone is sufficient for treatment of micro-invasive disease (Ia1) provided the margins are clear. The management of stage Ia2 d...

Invasive Aspergillosis in Cancer Patients

Dr. Bow has written a useful article summarizing many aspects of the present state of risk factors, prophylaxis, and prevention of invasive aspergillosis with additional comments about treatment. To amplify some of his points, I will look back over the last 5 years from the perspective of an article I wrote in 1995 for the Annales de Medecine Interne (the French equivalent to the Annals of Inte...

Malignant cancer and invasive placentation

Cancer metastasis is an invasive process that involves the transplantation of cells into new environments. Since human placentation is also invasive, hypotheses about a relationship between invasive placentation in eutherian mammals and metastasis have been proposed. The relationship between metastatic cancer and invasive placentation is usually presented in terms of antagonistic pleiotropy. Ac...

Invasive cancer cells and metastasis